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GB121130 Anti -SYT1 Mouse Monoclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse SYT1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB121130
  • Servicebio

Description

Product Information


Description

SYT1 mouse monoclonal

Protein full name

Synaptotagmin-1

Synonyms

Synaptotagmin I, SytI, p65, DKFZp781D2042, FLJ42519, SVP65, Syt2

Immunogen

Recombinant protein corresponding to Mouse SYT1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

47 kDa

Observed MW.

60 kDa

Uniprot ID

P21579, P46096





Applications



Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, cortex





Background


Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane. Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported.




Images


图片 1.png

Western blot analysis of SYT1 (GB121130)

at dilution of 1: 1000

Lane 1: SH-SY5Y cell lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse cortex tissue lysate

Lane 4: Rat brain tissue lysate

Lane 5: Rat cortex tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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