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GB121379 Anti -Synaptopodin Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Synaptopodin
Isotype:  IgG
Purity: Affinity purification
ul:
  • GB121379
  • Servicebio

Description

Product Information


Description Synaptopodin mouse monoclonal
Protein full name Synaptopodin
Synonyms Synpo, Kiaa1029
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse Synaptopodin
Isotype IgG
Purity Affinity purification
Predicted MW. 100 kDa
Observed MW. 100 kDa
Uniprot ID Q8CC35, Q9Z327




Applications


Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 cerebral cortex, brain, muscle




Background

SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene for synaptopodin do not form a spine apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.




Images



Western blot analysis of Synaptopodin  (GB121379) at dilution of 1: 1000
Lane 1: Mouse cerebral cortex tissue lysate
Lane 2: Mouse brain tissue lysate
Lane 3: Mouse muscle tissue lysate
Lane 4: Rat cerebral cortex tissue lysate
Lane 5: Rat brain tissue lysate
Lane 6: Rat muscle tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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