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GB12234 Anti -Connexin 43 / GJA1 Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12234
  • Servicebio

Description

Product Information



Description

Connexin 43 / GJA1 mouse monoclonal

Protein full name

Gap junction alpha-1 protein

Synonyms

GJA1, AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA, gap junction protein alpha 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43

Isotype IgG
Purity Affinity purification

Predicted MW.

43 kDa

Observed MW.

43 kDa

Subcellular location

Cell membrane, Cell junction,Endoplasmic reticulum

Uniprot ID

P17302, P23242, P08050




Applications



Applications

IHC

IF

Species

Mouse, Rat

Mouse, Rat

Dilution

1: 300-1: 600

1: 150- 1: 300

Positive tissue

heart

heart




Background


Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract . May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles .




Images



image.png

Immunofluorescence analysis of paraffin-embedded mouse heart using Connexin 43 (GB12234) at dilution of 1: 600

image.png

Immunofluorescence analysis of paraffin-embedded rat heart using Connexin 43 (GB12234) at dilution of 1: 600




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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