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GB12243 Anti -Hsp60 Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse HSP60
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12243
  • Servicebio

Description

Product Information


Description

HSP60 mouse monoclonal

Protein full name

60 kDa heat shock protein, mitochondrial

Synonyms

HSP60, HSP-60, HuCHA60, CPN60, 60 KDa Chaperonin, P60 Lymphocyte Protein, Heat Shock Protein 60

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse HSP60

Isotype IgG
Purity Affinity purification
Subcellular location

Cytoplasm

Predicted MW.

60 kDa

Observed MW.

60 kDa

Uniprot ID

P10809, P63039, P63038




Applications


Applications

WB

IHC

Species

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1: 500-1: 1000

1: 1000-1: 2000

Positive tissue

Hela, HepG2, MCF7, NIH/3T3, PC12

colon, colon cancer, kidney




Background


Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60’s bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetes, stress response, cancer and certain types of immunological disorders.




Images


Western blot analysis of HSP60 (GB12243) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: MCF7 cell lysate
Lane 4: NIH/3T3 cell lysate
Lane 5: PC12 cell lysate

Immunohistochemistry analysis of paraffin-embedded human colon using HSP60 (GB12243) at dilution of 1: 2000

IImmunohistochemistry analysis of paraffin-embedded human colon cancer using HSP60 (GB12243) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse kidney using HSP60 (GB12243) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat kidney using HSP60 (GB12243) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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