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GB12252 Anti -BMP2 Mouse Monoclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse BMP2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12252
  • Servicebio

Description

Product Information



Description

BMP2 mouse monoclonal

Protein full name

Bone morphogenetic protein 2

Synonyms

BMP2, BDA2, BMP2A,bone morphogenetic protein 2

Immunogen Recombinant protein corresponding to Mouse BMP2
Isotype IgG
Purity Affinity purification
Subcellular location

Secreted

Uniprot ID

P12643,P21274,P49001




Applications



Applications IHC,IF
Species

Rat

Dilution

1:500-1:1000

Positive tissue

bone




Background



Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.




Images



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Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 (GB12252) at dilution of 1:1000

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Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 (GB12252) at dilution of 1:1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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