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GB12333 Anti -HDAC1 Mouse Monoclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse HDAC1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12333
  • Servicebio

Description

Product Information


Description

HDAC1 mouse monoclonal

Protein full name

Histone deacetylase 1

Synonyms

HDAC1, GON-10, HD1, RPD3, RPD3L1, histone deacetylase 1

Immunogen

Recombinant protein corresponding to Mouse HDAC1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Predicted MW.

55 kDa

Observed MW.

62 kDa

Uniprot ID

Q13547O09106Q4QQW4



Applications


applications

species

dilution

Positive tissue

WB

Mouse, Rat

1: 500-1: 1000

testis, thymus

IHC

Human, Mouse, Rat

1: 1000-1: 2000

lung cancer, liver cancer, colon cancer, ovary cancer, heart, testis, brain, kidney

IF

Human, Mouse, Rat

1: 1000-1: 2000

small intestine cancer, colon, brain, lung, testis, kidney, heart




Background

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.




Images


Western blot analysis of HDAC1 (GB12333) at dilution of 1: 1000

Lane 1: NIH3T3 cell lysate

Lane 2: Mouse testis tissue lysate

Lane 3: Mouse thymus tissue lysate

Lane 4: Rat testis tissue lysate

Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human liver cancer using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human colon cancer using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human ovary cancer using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse heart using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse testis using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat testis using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse brain using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat brain using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse kidney using HDAC1 (GB12333) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat kidney using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human small intestine using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat colon using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat brain using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat lung using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat testis using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using HDAC1 (GB12333) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat heart using HDAC1 (GB12333) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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