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GB12548 Anti -Caspase-12 Mouse Monoclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse Caspase-12
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12548
  • Servicebio

Description

Product Information


Description Caspase-12 Mouse Monoclonal
Protein full name Caspase-12
Synonyms Casp12, CASP-12, CASP12P1, Inactive caspase-12, caspase 12 pseudogene 1, caspase 12 (gene/pseudogene)
Immunogen Recombinant protein corresponding to Mouse Caspase-12
Isotype IgG
Purity Affinity purification
Predicted MW. 48 kDa
Observed MW. 50 kDa
Uniprot ID O08736




Applications


Applications Species Dilution Positive Tissue
WB Mouse 1: 500-1: 1000 heart, lung,
skeletal muscle




Background


Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels.



Images


Western blot analysis of Caspase-12 (GB12548) at dilution of 1: 1000
Lane 1: NIH/3T3 cell lysate
Lane 2: L929 cell lysate
Lane 3: C2C12 cell lysate
Lane 4: Mouse heart tissue lysate
Lane 5: Mouse lung tissue lysate
Lane 6: Mouse muscle tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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