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GB13014 Anti -CD3 Rabbit Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to human CD3 epsilon
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13014
  • Servicebio

Description

Product Information



Description

CD3 rabbit monoclonal

Protein full name

T-cell surface glycoprotein CD3 epsilon chain

Synonyms

CD3E, IMD18, T3E, TCRE, CD3e molecule

Immunogen

KLH conjugated Synthetic peptide corresponding to human CD3 epsilon

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

P07766, P22646




Applications


applications

species

dilution

Positive tissue

IHC

Human, Mouse, Rat

1: 50-1: 200

spleen, liver

IF

Human, Mouse, Rat

1: 50-1: 200

spleen, liver




Background


The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.




Images


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Immunohistochemistry analysis of paraffin-embedded human spleen using CD3(GB13014) at dilution of 1:100.


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Immunohistochemistry analysis of paraffin-embedded mouse liver using CD3(GB13014) at dilution of 1:100.





Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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