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Anti -Collagen I Rabbit PAb For Western Blot polyclonal antibody

specification:50uL
  • GB13022-2
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description Collagen I rabbit polyclonal
Protein full name

Collagen alpha-1(I) chain

Synonyms

Collagen type I; Alpha 1 type I collagen;  Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide

Immunogen

KLH conjugated Synthetic peptide corresponding to Human Collagen alpha-1(I) chain

Isotype IgG
Purity Affinity purification

Predicted MW.

139 kDa

Observed MW.

125 kDa

Uniprot ID

P02452, P11087, P02454

 


 

Applications

 

 

Applications

WB

Species

Human, Mouse,Rat

Dilution

1:1000-1:2000

Positive tissue liver, ovary, lung

 


 

Background

 

 

Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

       


 

Images

 

 

GB13022-2.png

Western blot analysis of Collagen I (GB13022-2) at dilution of 1:1000.

Lane 1: NIH3T3 cell lysate

Lane 2: A431 cell lysate

Lane 3: 293 cell lysate

Lane 4: Mouse liver tissue lysate

Lane 5: Mouse ovary tissue lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Rat liver tissue lysate

Lane 8: Rat ovary tissue lysate

Lane 9: Rat lung tissue lysate

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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