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Anti -c-Myc Rabbit pAb for IHC IF

specification:50uL
  • GB13076
  • Servicebio
  • Servicebio

Description

Product Information



Description c-Myc rabbit polyclonal
Protein full name

Myc proto-oncogene protein

Synonyms

Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39
Immunogen

KLH conjugated Synthetic peptide corresponding to human Myc

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus

Uniprot ID

P01106, P01108, P09416




Applications



Applications

IHC/IF

Species

Human, Mouse, Rat

Dilution

1:100-1:200

Positive tissue

Liver cancer, breast cancer,lung




Background



C-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function.



Images



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Immunohistochemistry analysis of paraffin-embedded human liver cancer using c-Myc (GB13076) at dilution of 1:100


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Immunohistochemistry analysis of paraffin-embedded human breast  cancer using c-Myc (GB13076) at dilution of 1:100


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Immunohistochemistry analysis of paraffin-embedded mouse lung using c-Myc (GB13076) at dilution of 1:100





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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