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Anti -Fas Ligand Rabbit pAb for western blot

Specification:100uL
  • GB11090
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

Fas Ligand rabbit polyclonal

Protein full name

Tumor necrosis factor ligand superfamily member 6

Synonyms

Apoptosis antigen ligand, APTL, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD178, APT1LG1, CD95L, FASL, TNFSF6, FASLG, SPA

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630.1).

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane,Cytoplasmic vesicle lumen,Lysosome lumen,Nucleus,Secreted,Single-pass type II membrane protein

Predicted MW.

46 kDa

Observed MW.

14/31 kDa

Uniprot ID

P48023, P41047, P36940

 

 


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 2000

heart

 


 

Background

 

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

 


 

Images

 

   
   

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE: This product is intended for research only.

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