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Anti -PI 3 Kinase p85 alpha Mouse mAb for western blot primary antibody

specification:50uL
  • GB13161-1
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

PI 3 Kinase p85 alpha mouse monoclonal

Protein full name

Phosphatidylinositol 3-kinase regulatory subunit alpha

Synonyms

PIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA, phosphoinositide-3-kinase regulatory subunit 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PI 3 Kinase p85 alpha.

Isotype IgG
Purity Affinity purification

Predicted MW.

85 kDa

Observed MW.

80 kDa
Uniprot ID

P27986, P26450, Q63787

 


 

Applications

 

 

Applications

Species

dilution Positive tissue
WB

Human, Mouse, Rat

1:500-1:1000

muscle, heart,liver

 


 

Background

 

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

 


 

Images

 

 

image.png

Western blot analysis of PI 3 Kinase p85 alpha (GB13161-1) at dilution of 1:1000.

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: Jurkat cell lysate

Lane 4: Mouse muscle tissue lysate

Lane 5: Mouse heart tissue lysate

Lane 6: Mouse liver tissue lysate

Lane 7: Rat muscle tissue lysate

Lane 8: Rat heart tissue lysate

Lane 9: Rat liver tissue lysate

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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