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Anti -Beclin 1 Rabbit PAb For Western Blot Primary Antibody

Specification:100uL
  • GB112053
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description Beclin 1 rabbit polyclonal
Protein full name

Beclin-1

Synonyms

BECN1,ATG6,VPS30,beclin1,beclin-1, GT197
Immunogen

Recombinant protein corresponding to human beclin 1

Isotype IgG
Purity Affinity purification

Predicted MW.

52 kDa

Observed MW.

60 kDa
Uniprot ID

Q14457, Q91XJ1, O88597

 


 

Applications

 

 

Applications

WB

Species

Human,Mouse,Rat

Dilution 1:1000
Positive tissue brain

 


 

Background

 

Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer.

 


 

Images

 

 

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All lanes are rat brain tissue lysate Western blot analysis of Beclin 1 (GB13228-1) at dilution of 1:1000.

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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