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Anti -Beclin 1 Rabbit PAb for Western Blot Polyclonal Antibody

Specification:50uL
  • GB13228-2
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

Beclin 1 rabbit polyclonal

Protein full name

Beclin-1

Synonyms

BECN1, ATG6, VPS30, beclin1, beclin 1

Immunogen KLH conjugated Synthetic peptide corresponding to Human Beclin 1
Isotype IgG
Purity Affinity purification

Predicted MW.

50 kDa

Observed MW.

50 kDa
Uniprot ID

O88597, Q91XJ1

 


 

Applications

 

 

Applications

WB

Species

Mouse,Rat

Dilution

1:500-1:1000

Positive tissue heart, liver, brain

 


 

Background

 

 

Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer. Beclin 1 encodes an evolutionarily conserved 52kDa coiled coil protein that is expressed in human muscle, epithelial cells and neurons.

 


 

Images

 

 

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Western blot analysis of Beclin 1 (GB13228-2) at dilution of 1:1000.

Lane 1: Hela cell lysate

Lane 2: A549 cell lysate

Lane 3: MCF-7 cell lysate

Lane 4: Mouse heart tissue lysate

Lane 5: Mouse liver tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat heart tissue lysate

Lane 8: Rat liver tissue lysate

Lane 9: Rat brain tissue lysate

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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