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Anti -Connexin 43 / GJA1 Rabbit pAb For WB

Specification:50uL 
  • GB13234-1
  • Servicebio
  • Servicebio

Description

Product Information



Description

Connexin 43 rabbit polyclonal

Protein full name

Gap junction alpha-1 protein

Synonyms

GJA1, AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA, gap junction protein alpha 1

Immunogen

KLH conjugated Synthetic peptide corresponding to human Connexin 43

Isotype

IgG

Purity

Affinity purification

Predicted MW.

43 kDa

Observed MW.

43 kDa

Uniprot ID

P17302, P08050, P23242




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

Rat cell




Background



Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract . May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.




Images



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All lanes are rat cell lysate Western blot analysis of Connexin 43 (GB13234-1) at dilution of 1:1000.




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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