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Anti -CDK2 Rabbit PAb For Western Blot

Specification:50uL
  • GB13237
  • Servicebio
  • Servicebio

Description

Product Information


Description

CDK2 rabbit polyclonal

Protein full name

Cyclin-dependent kinase 2

Synonyms

Cell division protein kinase 2, p33 protein kinase, CDK2, CDKN2, CDC28, CDC2A, Cdc2 related protein kinase, p33(CDK2), MPF

Immunogen

KLH conjugated Synthetic peptide corresponding to human CDK2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

34 kDa

Observed MW.

34 kDa

Uniprot ID

P24941, Q63699, P97377




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse,Rat

1:500-1:1000

Lymph node, spleen, stomach




Background



This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, also known as Cdk1 in humans. It is a catalytic subunit of the cyclin-dependent kinase complex, whose activity is restricted to the G1-S phase of the cell cycle, and is essential[citation needed] for the G1/S transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin E or A. Cyclin E binds G1 phase Cdk2, which is required for the transition from G1 to S phase while binding with Cyclin A is required to progress through the S phase. Its activity is also regulated by phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.




Images



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All lanes are mouse mixed tissue lysate Western blot analysis of CDK2 (GB13237) at dilution of 1: 1000.




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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