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Anti -CD8 Rabbit mAb for mouse IHC

specification:50uL
  • GB13429
  • Servicebio
  • Servicebio

Description

Product Information

 

Description CD8 rabbit monoclonal
Protein full name T-cell surface glycoprotein CD8 alpha chain
Synonyms CD8A, CD8, Leu2, MAL, p32,CD8a molecule, CD8 alpha
Immunogen Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp42 of mouse CD8α protein
Isotype IgG
Purity Affinity purification
Subcellular location Cell membrane, Secreted
Uniprot ID P01731, P07725

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Mouse 1: 200-1: 800 tonsil

 


 

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene

 


 

Images

 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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