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Anti -Bcl-2 Mouse mAb For IHC TUNEL

Specification:50uL
  • GB13439
  • Servicebio
  • Servicebio

Description

Product Information

 

Description Bcl-2 Mouse monoclonal
Protein full name Apoptosis regulator Bcl-2
Synonyms Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, Bcl-2, Bcl2, BCL2_HUMAN, C430015F12Rik, D630044D05Rik
Immunogen Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.
Isotype IgG
Purity Affinity purification
Subcellular location Mitochondrion outer membrane, Nucleus membrane, Endoplasmic reticulum membrane
Uniprot ID P10415

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1: 50-1:200 breast carcinoma, salivary gland, UM xenografts

 


 

Background

BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.

 


 

Images

 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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