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Anti -CD3 Mouse mAb for IHC

Specification:50uL
  • GB13440
  • Servicebio
  • Servicebio

Description

Product Information

 

Description CD3 rabbit polyclonal
Protein full name T-cell surface glycoprotein CD3 epsilon chain
Synonyms T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
Immunogen Synthesized peptide derived from human CD3
Isotype IgG
Purity Affinity purification
Subcellular location Membrane
Uniprot ID P07766

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Human 1: 100-1:500 tonsil

 


 

Background

CD3e molecule(CD3E) Homo sapiens The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

 


 

Images

 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE: This product is intended for research only.

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