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GB13458 Anti -Bcl-2 Rabbit pAb Polyclonal

Immunogen: Synthetic peptide corresponding to Human Bcl-2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13458
  • Servicebio

Description

Product Information

 

DescriptionBcl-2 rabbit polyclonal
Protein full nameBCL2 Apoptosis Regulator
SynonymsApoptosis regulator Bcl 2,  Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, Bcl 2, Bcl-2, Bcl2, BCL2 protein, C430015F12Rik
ImmunogenSynthetic peptide corresponding to Human Bcl-2
IsotypeIgG
PurityAffinity purification
Predicted MW.26kDa
Observed MW.26kDa
Uniprot IDP10415

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 2000K562

 


 

Background

BCL2 belongs to the Bcl-2 family. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL2 regulates cell death by controlling the mitochondrial membrane permeability (PMID: 10365962). It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (PMID: 10444588). This antibody is not suitable for rat and mouse species.

 

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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