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GB13461 Anti -phospho-STAT3 Rabbit pAb Polyclonal

Immunogen: Synthesized peptide derived from human Stat3 around the phosphorylation site of S727
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13461
  • Servicebio

Description

Product Information

 

Descriptionphospho-STAT3rabbit polyclonal
Protein full namephospho-STAT3
SynonymsSTAT3 (phospho S727), p-STAT3 (phospho S727), STAT3(Phospho Ser727), STAT3(Phospho S727), p-STAT3(Ser727), Acute Phase Response Factor, APRF, DNA binding protein APRF, Signal Transductor and Activator of Transcription 3, STAT 3
ImmunogenSynthesized peptide derived from human Stat3 around the phosphorylation site of S727
IsotypeIgG
PurityAffinity purification
Predicted MW.88kDa
Observed MW.86kDa
Uniprot IDP40763

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman,Mouse,Rat,Monkey1: 1000-1: 5000Heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas

 


 

Background

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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