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GB13479 Anti -WNT1 Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse WNT1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13479
  • Servicebio

Description

Product Information

 

Description

WNT1 rabbit polyclonal

Protein full name

Wingless-Type MMTV Integration Site Family, Member 1

Synonyms

WNT1, BMND16, INT1, OI15

Immunogen

Recombinant protein corresponding to Mouse WNT1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted, Extracellular matrix, Extracellular space

Predicted MW.

40 kDa

Observed MW.

49 kDa

Uniprot ID

P04628


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 4000

liver, heart, kidney, liver


 

Background

Wnt proteins constitute a family of secreted glyocoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal. The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade. Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor. Extensive research has shown that deregulation of these pathways or its components can lead to cancer.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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