PHONE

+86(027) 5111 3188

Share to:

GB13497 Anti -ESR2 Rabbit pAb Antibody for Western Blot

Immunogen: ESR2 fusion protein Ag5103
Isotype: IgG
Purity: Antigen affinity purification
ul:
  • GB13497
  • Servicebio

Description

Product Information

 

Description

ESR2 rabbit polyclonal

Protein full name

estrogen receptor 2 (ER beta)

Synonyms

ER BETA, Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen receptor 2 (ER beta), Estrogen receptor beta, NR3A2

Immunogen

ESR2 fusion protein Ag5103

Isotype

IgG

Purity

Antigen affinity purification

Subcellular location

Nucleus

Predicted MW.

59 kDa

Observed MW.

55-60 kDa

Uniprot ID

Q92731


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 4000

NIH/3T3, SH-SY5Y,  brain, testis, PC-3, MCF-7


 

Background

Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. It binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. ESR2 exists various isoform and range of calculated molecular weight of isoforms is 50-60 kDa.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.