PHONE

+86(027) 5111 3188

Share to:

GB13501 Anti -RANKL Rabbit pAb Polyclonal Antibody

Immunogen: RANKL fusion protein Ag19975
Isotype: IgG
Purity: Antigen affinity purification
ul:
  • GB13501
  • Servicebio

Description

Product Information

 

Description

RANKL rabbit polyclonal

Protein full name

tumor necrosis factor (ligand) superfamily, member 11

Synonyms

CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoprotegerin ligand, RANKL, sOdf, TNFSF11, TRANCE

Immunogen

RANKL fusion protein Ag19975

Isotype

IgG

Purity

Antigen affinity purification

Subcellular location

Cytoplasm, Secreted, Cell membrane

Predicted MW.

35 kDa

Observed MW.

 

Uniprot ID

O35235


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

 

1: 200 -1: 1000

 

 

Background

TNFSF11 also known as RANKL, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. RANKL is a polypeptide of 217 amino acids that exerts its biological activity both in a transmembrane form of about 40-45 kDa and in soluble one of 31 kDa. RANKL was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. RANKL was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.