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GB13507 Anti -Amyloid-β Rabbit pAb Rabbit Derived Antibody

Immunogen: Synthesized peptide derived from Amyloid-β at AA range: 631-680
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13507
  • Servicebio

Description

Product Information

 

DescriptionAmyloid-β rabbit polyclonal
Protein full nameAmyloid-β
Synonymsmyloid beta A4 protein (ABPP) (APPI) (APP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP
ImmunogenSynthesized peptide derived from Amyloid-β at AA range: 631-680
IsotypeIgG
PurityAffinity purification
Subcellular locationCytoplasm, Nucleus, Secreted, Cell membrane
Predicted MW.87 kDa
Observed MW.86+45kDa
Uniprot IDP05067

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 2000 
ELISA 1:10000-1:20000 

 


 

Background

Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.


 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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