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GB13531 Anti -p-IRS-1 Rabbit pAb for Western Blot

Immunogen: A synthetic phosphorylated peptide around S307 of human IRS1 (NP_005535.1).
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13531
  • Servicebio

Description

Product Information

 

Descriptionp-IRS-1 rabbit polyclonal
Protein full nameInsulin receptor substrate 1
SynonymsIRS1, HIRS-1, insulin receptor substrate 1
ImmunogenA synthetic phosphorylated peptide around S307 of human IRS1 (NP_005535.1).
IsotypeIgG
PurityAffinity purification
Predicted MW.131 kDa
Observed MW.200 kDa
Uniprot IDP35568

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 2000brian

 


 

Background

Insulin receptor substrate 1 (IRS1) was the first cloned and characterized member of the IRS family which are involved in insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) signaling. IRS1 is phosphorylated by insulin receptor tyrosine kinase and is involved in various cellular processes including DNA repair fidelity, transcriptional activity, and cell growth can support tumor development and progression. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance .

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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