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GB13537 Anti -ATF6 Rabbit pAb Polyclonal

Immunogen: KLH conjugated synthetic peptide derived from human ATF6
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13537
  • Servicebio

Description

Product Information

 

DescriptionATF6 rabbit polyclonal
Protein full nameCyclic AMP-dependent transcription factor ATF-6 alpha
SynonymsActivating transcription factor 6 alpha, Activating transcription factor 6, ATF 6, ATF6 alpha, ATF6, ATF6-alpha, ATF6A, ATF6A_HUMAN, cAMP dependent transcription factor ATF 6 alpha
ImmunogenKLH conjugated synthetic peptide derived from human ATF6
IsotypeIgG
PurityAffinity purification
Predicted MW.75 kDa
Observed MW.75 kDa
Uniprot IDP18850

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 50-1: 200HeLa, MCF-7

 


 

Background

Activating transcription factor 6 (ATF6) is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor.During unfolded protein response an approximative 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis.

 

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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