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GB13540 Anti -Caspase 7/P20 Rabbit pAb

Immunogen: Caspase 7/p20 fusion protein Ag25904
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13540
  • Servicebio

Description

Product Information

 

DescriptionCaspase 7/P20 rabbit polyclonal
Protein full namecaspase 7, apoptosis-related cysteine peptidase
SynonymsApoptotic protease Mch 3, CASP 7, CASP7, Caspase 7, Caspase7, CMH 1, ICE LAP3, ICE like apoptotic protease 3, MCH3
ImmunogenCaspase 7/p20 fusion protein Ag25904
IsotypeIgG
PurityAffinity purification
Predicted MW.34 kDa
Observed MW.35 kDa
Uniprot IDP55210

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse1: 500-1: 1000Jurkat, HEK-293, LNCaP, MCF-7, PC-3

 


 

Background

Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, the 35 kDa proform is converted into a 32 kDa intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large (18 kDa) subunit and the p10 or small (11 kDa) subunit and it is present in the brain, which is up-regulated and activated after traumatic injury. Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9. The protein is involved in the activation cascade of caspases responsible for apoptosis execution.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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