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GB13543 Anti -P27 Rabbit pAb Antibody

Immunogen: P27, KIP1 fusion protein Ag22582
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13543
  • Servicebio

Description

Product Information

 

DescriptionP27rabbit polyclonal
Protein full namecyclin-dependent kinase inhibitor 1B (p27, Kip1)
SynonymsCDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27, P27, KIP1, P27KIP1
ImmunogenP27, KIP1 fusion protein Ag22582
IsotypeIgG
PurityAffinity purification
Predicted MW.22 kDa
Observed MW.27 kDa
Uniprot IDP46527

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Cow, Rat, Sheep1: 1000-1: 4000HepG2, HeLa, NIH/3T3, Jurkat

 


 

Background

CDKN1B, also named as P27 or KIP1, is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. P27 binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controlling cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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