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GB13546 Anti -Phospho-MEK1/2 Rabbit pAb Antibody

Immunogen: A synthesized peptide derived from human MEK1/2 around the phosphorylation site of Ser221.
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13546
  • Servicebio

Description

Product Information

 

DescriptionPhospho-MEK1/2 rabbit polyclonal
Protein full namePhospho-MEK1/2
SynonymsPhospho-MAP2K1, Phospho-MAP2K2
ImmunogenA synthesized peptide derived from human MEK1/2 around the phosphorylation site of Ser221.
IsotypeIgG
PurityAffinity purification
Predicted MW.44 kDa
Observed MW.45 kDa
Uniprot IDQ02750

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 2000Widely expressed, with extremely low levels in brain.

 


 

Background

MEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling. It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated. This antibody is specific to MEK1.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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