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GB13553 Western Blot Use Anti -OPG Rabbit pAb

Immunogen: KLH conjugated synthetic peptide derived from human OPG:221-300/401
Isotype: IgG
Purity: Affinity purification
ul:
  • GB13553
  • Servicebio

Description

Product Information

 

DescriptionOPN rabbit polyclonal
Protein full nameOPN
SynonymsMGC29565; OCIF; OPG; Osteoclastogenesis Inhibitory Factor; TNFRSF 11B; TNFRSF11B; TR 1; TR1; Tumor Necrosis Factor Receptor Superfamily Member 11b
ImmunogenKLH conjugated synthetic peptide derived from human OPG:221-300/401
IsotypeIgG
PurityAffinity purification
Predicted MW.43 kDa
Observed MW.43 kDa
Uniprot IDO00300

 


 

Applications

 

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 2000heart , kidney, liver, Raji, placenta, stomach

 


 

Background

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.

 


 

Storage

 

StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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