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Anti -Phospho-Tau Rabbit PAb for IHC Antibody

Specification: 50uL
  • GB13561
  • Servicebio
  • Servicebio

Description

Product Information

 

Description Phospho-Tau rabbit polyclonal
Protein full name Phospho-Tau (Ser214) Antibody
Synonyms AI413597, AW045860, DDPAC, FLJ31424, FTDP 17, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MGC134287, MGC138549, MGC156663, Microtubule associated protein tau
Immunogen A synthesized peptide derived from human Tau around the phosphorylation site of Ser214
Isotype IgG
Purity Affinity purification
Subcellular location Cytoplasm > cytosol. Cell membrane. Cytoplasm > cytoskeleton. Cell projection > axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Uniprot ID  

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1:500-1:2000 Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

 


 

Background

The microtubule-associated protein TAU (MAPT or TAU) is encoded by MAPT gene, which locates on human chromosome 17q21, binds to the tubulin subunit of microtubule and promotes its assembly and stability. Most TAU is expressed in neurons, and TAU isoform is expressed in the peripheral nervous system while the others are expressed in the central nervous system. TAU links axonal microtubules with C-terminus to neural plasma membrane components with its N-terminus, suggesting the participation in intracellular signal transduction and neuron's development and viability.

 


 

Images

 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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