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Anti -Klotho Rabbit PAb for Western Blot Antibody

Specification:50uL
  • GB13578
  • Servicebio
  • Servicebio

Description

Product Information

 

Description Klotho rabbit polyclonal
Protein full name Klotho
Synonyms KL antibody, Klotho peptide
Immunogen KLH conjugated synthetic peptide derived from human Klotho:401-500/1012
Isotype IgG
Purity Affinity purification
Predicted MW. 113 kDa
Observed MW. 113 kDa
Uniprot ID Q9UEF7

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 1000 kidney, fetal kidney, testis, fetal thymus

 


 

Background

KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling.

 


 

Images

 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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