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Anti -Caldesmon/CDM Mouse mAb For human IHC IF Monoclonal Antibody

Specification:50uL
  • GB14015
  • Servicebio
  • Servicebio

Description

Product Information


Gene Name CALD1 CAD CDM
Protein Name Caldesmon (CDM)
Human Gene Id 800
Human Swiss Prot No Q05682
Immunogen Synthesized peptide derived from human  Caldesmon
Specificity This antibody detects endogenous levels of human  Caldesmon
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],




Images



Immunohistochemical analysis of paraffin-embedded Fibroid. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Liomyoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE: This product is intended for research only.

Laboratory(1)downLoadImgSlice 13Slice 10Slice 12

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