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Anti -CD1a Mouse mAb

  • Servicebio

Description

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Product Information

Gene Name CD1A
Protein Name T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)
Human Gene Id 909
Human Swiss Prot No P06126
Immunogen Synthesized peptide derived from human CD1a
Specificity This antibody detects endogenous levels of human CD1a
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.


Applications

Applications Species Dilution
IHC、IF Human 1:200-1:500


Background

CD1A encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1a molecule encoded by CD1A localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.


Images


Immunohistochemical analysis of paraffin-embedded Thymoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citrate buffer of pH6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Thymoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citrate buffer of pH6.0 was used for antigen retrieval.


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


NOTE: This product is intended for research only.

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