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Anti -Cytokeratin 19 Mouse MAb for Human IHC IF Research

Specification: 50uL
  • GB14058
  • Servicebio
  • Servicebio

Description

Product Information


Gene Name KRT19
Protein Name Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Human Gene Id 3880
Human Swiss Prot No P08727
Immunogen Synthesized peptide derived from human Cytokeratin 19
Specificity This antibody detects endogenous levels of human Cytokeratin 19
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

keratin 19 encoded by KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.




Images



Immunohistochemical analysis of paraffin-embedded Kindey. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Appendix. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE: This product is intended for research only.

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