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Anti -Cytokeratin 8 Mouse MAb IHC IF Monoclonal Antibody

Specification:50ul
  • GB14065
  • Servicebio
  • Servicebio

Description

Product Information


Gene Name KRT8 CYK8
Protein Name Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Human Gene Id 3856
Human Swiss Prot No P05787
Immunogen Synthesized peptide derived from human Cytokeratin 8
Specificity This antibody detects endogenous levels of human Cytokeratin 8
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],




Images



Immunohistochemical analysis of paraffin-embedded Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Hepatocellular carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE: This product is intended for research only.

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