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Anti -Claudin 3 Mouse MAb For IHC IF Monoclonal Antibodies

Specification: 50uL
  • GB14069
  • Servicebio
  • Servicebio

Description

Product Information


Gene Name CLDN3 C7orf1 CPETR2
Protein Name Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1)
Human Gene Id 1365
Human Swiss Prot No O15551
Immunogen Synthesized peptide derived from human Claudin 3
Specificity This antibody detects endogenous levels of human Claudin 3
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

claudin 3(CLDN3) Homo sapiens Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008],




Images



Immunohistochemical analysis of paraffin-embedded Colon. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Colon. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE: This product is intended for research only.

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