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Anti -Myelin Basic Protein Mouse MAb for IHC IF Monoclonal Antibody

Specification: 50uL
  • GB14114
  • Servicebio
  • Servicebio

Description

Product Information


Gene Name MBP
Protein Name Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)
Human Gene Id 4155
Human Swiss Prot No P02686
Immunogen Synthesized peptide derived from human  Myelin Basic Protein(MBP)
Specificity This antibody detects endogenous levels of human  Myelin Basic Protein(MBP)
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

myelin basic protein(MBP) Homo sapiens The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that




Images



Immunohistochemical analysis of paraffin-embedded Brain. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Brain. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE: This product is intended for research only.

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