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Anti -68kDa Neurofilament/NF-L Mouse mAb for IHC IF Research antibodies

Specification: 50uL
  • GB14120
  • Servicebio
  • Servicebio

Description

Product Information


Gene Name NEFL NF68 NFL
Protein Name Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Human Gene Id 4747
Human Swiss Prot No P07196
Immunogen Synthesized peptide derived from human Neurofilament
Specificity This antibody detects endogenous levels of human Neurofilament
Source Mouse/IgG2b, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

neurofilament, light polypeptide(NEFL) Homo sapiens Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008],




Images



Immunohistochemical analysis of paraffin-embedded Brain. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Brain. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE: This product is intended for research only.

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