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GB11226-1 Anti -Myelin Basic Protein Rabbit pAb

Immunogen: Recombinant protein corresponding to Mouse Myelin Basic Protein
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11226-1
  • Servicebio

Description

Product Information

 

 

Description

Myelin Basic Protein rabbit polyclonal

Protein full name

Myelin Basic Protein

Synonyms

MBP, entrez:4155, myelin basic protein

Immunogen

Recombinant protein corresponding to Mouse Myelin Basic Protein

Isotype IgG
Purity Affinity purification
Subcellular location

Myelin membrane, Cytoplasmic side of myelin

Uniprot ID

P04370P02688

 


 

Applications

 

 

Applications

IHC, IF

 
Species

Mouse, Rat

 
Dilution

1:500-1:2000

 
Positive tissue

Brain

 

 


 

Background

 

The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.

     


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded mouse brain using Myelin Basic Protein (GB11226-1) at dilution of 1:1600

 

   

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Immunohistochemistry analysis of paraffin-embedded rat brain using Myelin Basic Protein (GB11226-1) at dilution of 1:800

 

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