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GB11192 Affinity Purification Anti-Vimentin Rabbit pAb

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse vimentin
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11192
  • Servicebio

Description

Product Information

 

Description

Vimentin rabbit polyclonal

Protein full name

Vimentin

Synonyms

VIM, CTRCT30, HEL113, vimentin

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse vimentin 

Isotype IgG
Purity Affinity purification
Predicted MW.

57KDa

Observed MW.

57KDa

Subcellular location

Cytoplasm

Uniprot ID

P08670P20152P31000

 


 

Applications

 

Applications

WB

IHC

IF

Species

Human, Mouse, Rat

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1:500-1:1000

1:500-1:1000

1:200-1:500

Positive tissue

Hela, HepG2, SW480, PC12,lung

Liver cancer, kidney

Kidney, lung

 


 

Background

 

Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprises the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression.

 


 

Images

 

blob.png

Western blot analysis of Vimentin (GB11192) at dilution of 1:1000.

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: SW480 cell lysate

Lane 4: B16 cell lysate

Lane 5: PC12 cell lysate

Lane 6: Mouse lung tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded human liver cancer using Vimentin (GB11192) at dilution of 1:1000

image.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using Vimentin (GB11192) at dilution of 1:1000


Storage:


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


Publications:



Title

Journal

Pubmed ID

Application

1

Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.

Journal of Cellular and Molecular Medicine

31797546

WB

2

CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.

Cell Death & Disease

31827075

WB

3

Tacrolimus increases the expression level of the chemokine receptor CXCR2 to promote renal fibrosis progression.

International Journal of Molecular Medicine

31638188

IHC

4

Bioinformatics analysis of LINC01554 and its co-expressed genes in hepatocellular carcinoma.

Oncology Reports

33000250

WB

5

Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.

Molecular Cell

31812350

WB

6

Immunohistochemical biomarkers and distribution of telocytes in ApoE-/- mice.

Cell Biology International

30912221

IHC

7

Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling.

Cells

31416135

IHC

8

Transcriptomics analysis of sirolimus treatment in lupus nephritis.

Molecular Medicine Reports

31115581

/

9

Baicalein suppress EMT of breast cancer by mediating tumor-associated macrophages polarization.

American Journal of Cancer Research

30210921

IHC,WB


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