GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development, during axonal regeneration and is phosphorylated after long-term potentiation(LTP) and after learning (reference needed). This protein is considered a crucial component of the axon andpresynaptic terminal, its null mutation leading to death within days after birth due to axon pathfinding defects.
Western blot analysis of GAP43 (GB11095) at dilution of 1:2000.
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: SW480 cell lysate
Lane 4: Mouse heart tissue lysate
Lane 5: Mouse brain tissue lysate
Lane 6: Rat brain tissue lysate
Immunohistochemistry analysis of paraffin-embedded mouse brain using GAP43 (GB11095) at dilution of 1:600
Immunohistochemistry analysis of paraffin-embedded rat brain using GAP43 (GB11095) at dilution of 1:600