Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.
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Western blot analysis of GABA A Receptor alpha 1 (GB11561) at dilution of 1:800.
Lane 1: U87 cell lysate
Lane 2: U251 cell lysate
Lane 3: SH-SY5Y cell lysate
|Storage ||Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
|Storage Buffer ||PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.