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Anti -Connexin 43 / GJA1 Mouse mAb for Mouse Rat Immunoblotting antibody

Specification:100ul
  • GB12234
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

Connexin 43 / GJA1 mouse monoclonal

Protein full name

Gap junction alpha-1 protein

Synonyms

GJA1, AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA, gap junction protein alpha 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43

Isotype IgG
Purity Affinity purification

Predicted MW.

43 kDa

Observed MW.

43 kDa

Subcellular location

Cell membrane, Cell junction, Endoplasmic reticulum

Uniprot ID

P17302P23242P08050

 


 

Applications

 

 

Applications

IHC

IF

 
Species

Mouse, Rat

Mouse, Rat

 
Dilution

1: 300-1: 600

1: 150- 1: 300

 
Positive tissue

heart

heart

 

 


 

Background 

 

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.      

     


 

Images

 

 

image.png  

Immunofluorescence analysis of paraffin-embedded mouse heart using Connexin 43 (GB12234) at dilution of 1: 600

     
image.png  

Immunofluorescence analysis of paraffin-embedded rat heart using Connexin 43 (GB12234) at dilution of 1: 600

Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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