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Anti -CytokeRin 8 Mouse MAb for Human Mouse Rat Immunoblotting Antibody

Specification:100ul
  • GB12231
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

CytokeRin 8 mouse monoclonal

Protein full name

Keratin, type II cytoskeletal 8

Synonyms

KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, keratin 8

Immunogen

Recombinant protein corresponding to Mouse Cytokeratin 8

Isotype IgG
Purity Affinity purification
Subcellular location

cytoplasm, Nucleus matrix, Cytoplasm

Uniprot ID

P05787,P11679,Q10758

 


 

Applications

 

 

Applications IHC, IF  
Species Human, Mouse, Rat  
Dilution 1:100-1:200  
Positive tissue Stomach, liver  

 


 

Background

 

 

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

 


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded human stomach cancer using Cytokeratin 8 (GB12231) at dilution of 1:100.

   

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Immunohistochemistry analysis of paraffin-embedded mouse stomach cancer using Cytokeratin 8 (GB12231) at dilution of 1:100.

   

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Immunohistochemistry analysis of paraffin-embedded rat stomach using Cytokeratin 8 (GB12231) at dilution of 1:100.

   

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Immunohistochemistry analysis of paraffin-embedded rat liver using Cytokeratin 8 (GB12231) at dilution of 1:100.

Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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