PHONE

+86(027) 5111 3188

Share to:

Anti -Fas Mouse mAb for Human Mouse IHC IF

Specification:100ul
  • GB12089
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

Fas mouse monoclonal

Protein full name

Tumor necrosis factor receptor superfamily member 6

Synonyms

FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse FAS
Isotype IgG
Purity Affinity purification
Subcellular location

Cell membrane, Secrete

Uniprot ID

P25445P25446

 


 

Applications

 

 

Applications

IHC, IF

   
Species

Human, Mouse

   
Dilution

1:200-1:800

   
Positive tissue

Gallbadder, colon

   

 


 

Background

 

 

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

     


 

Images

 

 

blob.png

Immunohistochemistry analysis of paraffin-embedded human gallbladder  using FAS (GB12089) at dilution of 1:200

   

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse colon  using FAS (GB12089) at dilution of 1:400

   
blob.png

Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS (GB12089) at dilution of 1:400

Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

downLoadImgSlice 10Slice 12Slice 13

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.