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Anti -ERK1+ ERK2 Mouse mAb for Human Rat Mouse Western Blot

Specification:100ul
  • GB12087
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

ERK1+ ERK2 mouse monoclonal

Protein full name

Mitogen-activated protein kinase 1

Synonyms

MAPK1, ERK,ERK-2,ERK2, ERT1, MAPK2, P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,p42-MAPK,mitogen-activated protein kinase 1

Immunogen

Recombinant protein corresponding to Mouse ERK2

Isotype IgG
Purity Affinity purification
Predicted MW.

42/44KDa

Observed MW.

42/44KDa

Uniprot ID

P63085P63086P28482P27361P21708Q63844

 


 

Applications

 

 

Applications

WB

   
Species Human, Rat, Mouse    
Dilution 1: 500-1: 1000    
Positive tissue Hela, HepG2, NIH/3T3, lung, kidney, brain    

 


 

Background

 

 

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

     


 

Images

 

 

blob.png

Western blot analysis of ERK1/2 (GB12087) at dilution of 1:1000.

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: NIH/3T3 cell lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Mouse kidney tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8: Rat kindy tissue lysate

Lane 9: Rat brain tissue lysate

Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

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